Dyskinesia (the presence of involuntary movements) is a well
known complication of long term levodopa therapy.
The dyskinesias are often considered more bothersome to the
family members (and health care providers) than they are to the patients.
One possible way to lessen the extent of dyskinesia is a
levodopa dose reduction. However, this often results in worsening of
parkinsonism symptoms and increasing “off” periods.
It’s important to remember that patients often prefer
the mobility associated with dyskinesias to the immobility associated with no
dyskinesias.
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